Ask before choosing an endpoint
Movement, communication, comfort, and participation can mean different things to different people. Choosing what to measure should start with listening.
Be specific about change
An outcome must distinguish a meaningful change from ordinary variation, measurement noise, or an effect that matters only in a test setting. Safety and the burden of treatment belong in the same conversation.
Keep the person in view
The imagined Kitheras model includes accessible communication, thoughtful study logistics, and attention to quality of life alongside clinical measurements. These are design commitments, not results from a real Kitheras study.
This editorial accompanies a hypothetical company vision. It does not announce research results or establish clinical guidance.
Scientific background & sources ↗